Virginia Commonwealth University researchers developed a novel technique to detect and identify patients with Overactive Bladder (OAB). The technology can be readily used with existing equipment. The application of this software helps increase the ability to detect Overactive Bladder syndrome and Detrusor Overactivity (DO). Current methodologies depend on urodynamics testing by filling the bladder with an invasive catheter. Dr. Speich’s novel system would allow for invasive or non-invasive micromotion and bladder width testing.

The technology

A novel automated algorithm utilizes fast Fourier transforms to analyze a region of interest. The software can then measure relative bladder thickness, pressure and micromotion in order to help diagnose OAB and DO in a non-invasive manner. Existing laboratories can easily adopt this technique using standard equipment.

Physicians and Urologists can use this technology as an alternative to trans-vaginal probing. In addition to reducing pain or stress on the patient, this technology can be integrated into a urodynamics system to provide real-time analysis of bladder wall micromotion to a physician.  These measurements provide supplemental information to be used in the urodynamics system in order to better diagnose DO and OAB. The micromotion measurements provide the ability to identify different patient sub-groups for targeted treatments and novel drug trials. VCU is seeking market insights on commercialization of this bladder thickness and micromotion detection software. We welcome interest from potential partners and licensees.

Figure 1: Bladder thickness measurement during filling and unfilling of bladder