Acoustic-Based Tissue Resuscitation

The technology

Market need

Current methods used to treat and prevent ischemia consist of intravenously-delivered pharmaceutical agents and invasive devices, such as the intra-aortic balloon pump. The ability to modulate blood flow easily and noninvasively is necessary for adequate treatment and prevention of ischemia.

Technology summary

This is a device to treat or prevent ischemia by rapidly increasing blood flow and, thereby, oxygen to tissues. The device delivers a low-frequency sound to the entire body or selected areas, which results in an increase in blood flow. The device is non-invasive and the effect can essentially be turned on and off. Moreover, this device could allow on-thefly programming and feedback when coupled with a method or technique which measures tissue oxygenation or blood flow. The apparatus is user-friendly and could be used by paramedics or in emergency departments, operating rooms, intensive care units, and in the home.

Chart showing acoustical modulation of blood flow

Technology status

Pilot animal studies are underway.