Research Tool

Anti-CtBP1 [CG14] Antibody

The technology

CtBP1 functions as a transcriptional compressor. CtBPs regulates epithelial to mesenchymal transition and cell metabolism. Due to the unavailability of commercial antibodies against human C-terminal-binding protein 1 (CtBP1), inventors at Virginia Commonwealth University have developed mouse monoclonal antibodies against this protein. Successful screening of the antibodies were performed by Western Blot (WB) analysis using CtBP1-His and the human ovarian cancer cell line SKOV3 as a source of material. The antibodies were also successfully tested in immunoprecipitation assays (IP), immunofluorescence cell staining (IHC), and chromatin immunoprecipitation assays (ChIP).

  •  Antigen/Gene or Protein Targets
    • CtBP1 (does not cross-react with CtBP2)
  •  Reactivity
    • Human
  •  Host
    • Mouse
  •  Immunogen
    • Full length protein C-terminal 6xHis-tag
  • Subclass
    • IgG2a kappa